The Anti-Mouse CD4 APC (Clone CT-CD4) (rat IgG2a) Antibody from MyBioSource.com is a Mouse Monoclonal antibody to CD4, L3T4, LEU3, and W3/25. This antibody recognizes Human, and Mouse antigen. The Anti-Mouse CD4 APC (Clone CT-CD4) (rat IgG2a) Antibody has been validated for the following applications: Immunohistochemistry.
Description
This monoclonal antibody (mAb) recognizes mouse CD4 (L3T4) which is expressed on the majority of thymocytes and on the MHC class II restricted subset of mature T cells including Th cells1,2. Mouse CD4 has also been reported to be present on multipotential hematopoietic stem cells, bone marrow myeloid precursors, and intrathymic precursors2,3. As a coreceptor in the TCR complex, CD4 is involved in T cell activation through interaction with MHC class II on APC's and in signal transduction via protein tyrosine kinase lck1. This antibody is suitable for use in flow cytometry and is reported to work in immunohistochemistry on acetone fixed frozen sections